Are you a physician interested in Platelet Rich Plasma information?  We have compiled all of the information you might find valuable in regards to PRP right here in one spot for physicians.

Questions from Doctors Answered by Doctors

  • Must we activate platelets for knee injection? We active PRP with Ca gloconate in IRAN but I read in some books we can inject PRP without activator in joints. I want to know which is better or safer?  How many kits do we use for every knee? Some doctors say we use 2 kits of PRP and the other says 1 kit of PRP.  Because I do PRP for skin and the volume is not a problem for us, we can use 1 or 2 kits for skin and hair but in joints for a knee exam, how much volume we can inject?

This response was given by Dr. Arockia Doss one of our physician specialty experts.

  1. I do not activate Platelets at all for any of my musculoskeletal injections as I wish to keep it as natural as possible. Personally I think this is a safer approach. It works anyway!
  2. As a standard I take 12 to 16 cc of blood and mix the PRP and PPP in 5 cc of 1% lignocaine for one knee joint. This comes to a total volume of around 15cc of total injectate. I warn of stiffness for a few days, pain crisis has not occurred in my experience in joints. For smaller joints I just half this.
  3. I am moving more and more towards 3 injections spaced 4 weeks apart with an annual cycle.

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