Is PRP a better option than just doing physical therapy or surgery for a severe ankle sprain? And, if you think it is more effective, what makes it more effective?

A sprain is a ligament injury and PRP has been shown to be effective for ligament injuries.  Most routine ankle sprains don’t require PRP treatment, but PRP can certainly aid in the healing and may speed up recovery time.  PRP can also be used in chronic ankle sprains that fail routine treatment.

For severe ankle sprains with significant instability or involvement of the syndesmosis, PRP may not be appropriate and surgery may be required.  A thorough evaluation and appropriate imaging should be performed to determine the necessary treatment.

This question was answered by Dr. Andrew Blecher, MD